Know more

About cookies

What is a "cookie"?

A "cookie" is a piece of information, usually small and identified by a name, which may be sent to your browser by a website you are visiting. Your web browser will store it for a period of time, and send it back to the web server each time you log on again.

Different types of cookies are placed on the sites:

  • Cookies strictly necessary for the proper functioning of the site
  • Cookies deposited by third party sites to improve the interactivity of the site, to collect statistics

Learn more about cookies and how they work

The different types of cookies used on this site

Cookies strictly necessary for the site to function

These cookies allow the main services of the site to function optimally. You can technically block them using your browser settings but your experience on the site may be degraded.

Furthermore, you have the possibility of opposing the use of audience measurement tracers strictly necessary for the functioning and current administration of the website in the cookie management window accessible via the link located in the footer of the site.

Technical cookies

Name of the cookie


Shelf life

CAS and PHP session cookies

Login credentials, session security



Saving your cookie consent choices

12 months

Audience measurement cookies (AT Internet)

Name of the cookie


Shelf life


Trace the visitor's route in order to establish visit statistics.

13 months


Store the anonymous ID of the visitor who starts the first time he visits the site

13 months


Identify the numbers (unique identifiers of a site) seen by the visitor and store the visitor's identifiers.

13 months

About the AT Internet audience measurement tool :

AT Internet's audience measurement tool Analytics is deployed on this site in order to obtain information on visitors' navigation and to improve its use.

The French data protection authority (CNIL) has granted an exemption to AT Internet's Web Analytics cookie. This tool is thus exempt from the collection of the Internet user's consent with regard to the deposit of analytics cookies. However, you can refuse the deposit of these cookies via the cookie management panel.

Good to know:

  • The data collected are not cross-checked with other processing operations
  • The deposited cookie is only used to produce anonymous statistics
  • The cookie does not allow the user's navigation on other sites to be tracked.

Third party cookies to improve the interactivity of the site

This site relies on certain services provided by third parties which allow :

  • to offer interactive content;
  • improve usability and facilitate the sharing of content on social networks;
  • view videos and animated presentations directly on our website;
  • protect form entries from robots;
  • monitor the performance of the site.

These third parties will collect and use your browsing data for their own purposes.

How to accept or reject cookies

When you start browsing an eZpublish site, the appearance of the "cookies" banner allows you to accept or refuse all the cookies we use. This banner will be displayed as long as you have not made a choice, even if you are browsing on another page of the site.

You can change your choices at any time by clicking on the "Cookie Management" link.

You can manage these cookies in your browser. Here are the procedures to follow: Firefox; Chrome; Explorer; Safari; Opera

For more information about the cookies we use, you can contact INRAE's Data Protection Officer by email at or by post at :


24, chemin de Borde Rouge -Auzeville - CS52627 31326 Castanet Tolosan cedex - France

Last update: May 2021

Menu Logo Principal INRAE Université de Liège Université de Lille Université Picardie Jules Verne Associated institutions

UMR Transfrontalière BioEcoAgro (

Thesis: Implication of swertisin and swertiajaponin in cold stress tolerance of flax

ESTABLISHMENT : University of Lille, Faculty of Sciences and Technologies

Laboratory(ies) of affiliation : UMRT INRAE 1158 BioEcoAgro

Scientific field, Speciality: DS10 | Food Biotechnology, Food Science, Physiology

Thesis director: Gagneul, David, Lecturer,

Co-supervisor (non HDR): Quéro, Anthony, Lecturer,

Planned (co)-funding : Région Hauts-de-France (in progress, 50%) et ED 104 SMRE (in progress, 50%)

Title of the thesis : Implication of swertisin and swertiajaponin in cold stress tolerance of flax (Linum usitatissimum L.)


Global warming is associated with a progressive increase in the frequency of climatic accidents. In order to mitigate this evolution and maintain an agricultural production that meets the needs of our societies, it will be necessary to modify the cultivation practices of field crops. To adapt to tomorrow's environment and ensure the ecological and environmental transition, the use of new varieties represents a relevant approach. Thus, for fiber flax, a species of regional interest, the creation of winter varieties is a judicious solution. Sown at the end of September, winter flax takes root during the fall and is well established in the spring when vegetation resumes. Its well-developed root system allows it to draw water from deep within the soil and to be more tolerant than spring flax during unfavorable spring rainfall (as in 2022). Also, its earlier maturity than spring flax, allows it to be pulled out earlier (beginning of June) and to be less exposed to the dry conditions of the summer.

Despite these advantages, the number of available winter flax varieties is still limited and the lack of information on the mechanisms involved in cold tolerance in flax slows down varietal selection. Thus, the lack of biomarkers restricts breeders in their approach and the breeding of these varieties relies today on empirical methods. Two potential markers for winter wheat have recently been identified: C-glycoside flavones. The objective of this thesis is to definitively determine the role of these molecules in cold tolerance and thus provide breeders with tools to assist in selection.

A candidate gene, LuOMT1, whose product would be involved in the last step of the synthesis of these flavone C-glycosides, has been recently identified and cloned in the laboratory. The first step will be to validate the involvement of the product of this gene in the synthesis of flavone C-glycosides (biochemical role). The recombinant protein will be produced in different heterologous systems, purified and its catalytic parameters determined. Then, through genome editing of spring and winter flax varieties (overexpression or gene silencing), the involvement of the molecules in cold tolerance will be validated (physiological role). The genetic modifications induced should lead to metabolic modifications and the impact of these modifications will be apprehended through the monitoring of acclimatization and cold tolerance of genetically modified lines.

Expected date of recruitment: october 1st 2023

Contact: and